Rejuran Korea before and after changes are slower and quieter than those of most other skin boosters, so they are easy to misread when set beside hyaluronic acid (HA) or PDLLA results. Rejuran is a polynucleotide (PN) injectable, not PDRN, placed at roughly 200 to 300 small points per full-face session. An HA booster tends to show plumper, dewier skin within days. PN aims at texture, fine lines and a sturdier feel, which build across a course of visits spaced about 7 to 10 days apart and commonly last four to six months. A fair comparison therefore looks at the same skin months apart, not days. Expect raised bumps, redness and possible bruising first. Results vary from person to person.
Guide
How the timeline of PN differs from HA and PDLLA
Each booster family changes the skin on its own clock, so photo pairs taken at the same interval can flatter one and undersell another. HA boosters hold water, so change often shows once the bumps settle. PDLLA boosters such as Juvelook build collagen gradually over months. PN sits between them: no instant plumping, with texture and fine crinkling improving over a series.
Exosome solutions in Korea are applied to the skin after microneedling rather than injected, so their photos mostly reflect the needling session.
| Booster family | What it mainly targets | When change is usually judged | What a photo can show |
|---|---|---|---|
| PN (Rejuran) | Texture, fine lines, skin that feels thin | After a course, weeks after the last visit | Smoother surface, less crinkling under raking light |
| HA booster | Hydration and glow | Days to a couple of weeks after a session | Dewier reflection, softer fine dryness lines |
| PDLLA (Juvelook) | Gradual firmness and density | Over several months | Subtle change in contour and skin thickness |
| Exosome after microneedling | Recovery after the needling step | Alongside the microneedling result | Mostly the effect of the needling itself |
Guide
What a published PN study measured over six months
The clearest timeline data for PN comes from outcome scores rather than photos. Ziade and colleagues, in a 2026 prospective observational study in the Journal of Cosmetic Dermatology, followed 42 patients who had intradermal PN injections under the eyes. They used validated FACE-Q questionnaires at baseline and at 1, 3 and 6 months.
Lower eyelid and crow's feet scores improved at every follow-up point compared with baseline, and the largest improvement and highest satisfaction were seen at 3 months, after two sessions. Reported adverse events were minimal. The product was a PN gel from a European maker, not Rejuran, so the pattern is informative about PN in general rather than about one brand.
Guide
Checks before trusting any clinic photo pair
Because PN changes are subtle, small shifts in setup can create a difference that is not really there. Look at the conditions before looking at the skin.
- Same light direction and strength on both sides; side light exaggerates texture
- Same camera distance, angle and lens; a closer shot shows more pores
- Same expression and head tilt; a slight smile changes crow's feet
- No makeup, filter or retouching on either image
- Dates shown, with the after image taken weeks after the last session
- A note of which product line and how many sessions were used
Guide
Why the name on the label affects the comparison
DNA-derived boosters are often grouped together, which blurs what a photo set is really showing. Marques and colleagues, in a 2025 review in Biomolecules, pointed out that the terms PDRN and PN are used interchangeably in the literature for polymers of very different chain lengths, and proposed reserving PN for longer chains. A gallery labeled as a DNA booster may therefore mix products with different behavior.
When a clinic shows a pair, ask which exact product was injected. A PDRN serum, an HA blend or another PN brand does not predict what Rejuran Healer, HB Plus or the eye-area line will do.
Guide
The marks that come before any improvement
The first days after a PN session look worse, not better. Raised bumps at the injection points usually settle within one to three days, while redness, mild swelling and small bruises can take longer, with bruises sometimes lasting about a week. Rare risks include lumps that persist, infection and allergic reaction, and people with an allergy to fish-derived products should raise it before treatment.
That is why a fair record skips the first week. Pregnancy, active facial infection or a bleeding disorder are reasons to discuss waiting.
Evidence
Research behind this page
- From Polydeoxyribonucleotides (PDRNs) to Polynucleotides (PNs): Bridging the Gap Between Scientific Definitions, Molecular Insights, and Clinical Applications of Multifunctional BiomoleculesBiomolecules · 2025 · doi:10.3390/biom15010148
Narrative review noting that PDRN and PN are used interchangeably for DNA polymers of very different sizes and proposing a 1500 kDa cutoff to separate the two terms.
- Prospective Observational Study of Polynucleotide Injections for Periorbital RhytidesJournal of Cosmetic Dermatology · 2026 · doi:10.1111/jocd.70736
Case series of 42 patients receiving intradermal polynucleotide injections under the eyes, with FACE-Q scores improved at 1, 3 and 6 months and the largest gain at 3 months after two sessions.
FAQ
Questions about Skin boosters in Gangnam
Should I take my own photos instead of relying on the clinic's?
Yes, a simple personal record is often more useful than any gallery because it shows your own skin under conditions you control. Take a front view and both sides before the first injection, by the same window at the same time of day, without makeup. Repeat the set before each later visit and several weeks after the last one, at the same camera distance.
Can PN and an HA booster be judged in the same photo set?
Not easily, because the two act on different timelines and a combined result cannot be split afterward. HA tends to show hydration within days, while PN changes in texture build across a course. If both are used in one plan, note the dates of each product so later photos can be read against them. Someone who wants to see what PN alone does may prefer to run a PN course first and add other boosters later.
How long do PN changes last before photos drift back?
Effects commonly last about four to six months, after which skin gradually returns toward its earlier state. Timing depends on age, sun exposure, skincare and the number of sessions, and many people plan a maintenance visit within that window. Photos a year after a single course often look close to the original set, which is expected. Results vary from person to person.
Does the eye-area product show change differently from the face product?
It is designed for thin skin like the under-eye area, so its effect is judged on fine crinkling there rather than on the whole face. Under-eye photos are especially sensitive to light and expression, since a slight squint deepens lines. Ask the doctor which product line suits the area. When comparing images, look at the same zone at rest, with the eyes open in the same way on both dates.
Is it normal to see little change after the first session?
Yes, a small or no visible change after one PN session is common, because the effect builds across a series. The first week is also dominated by bumps and redness, which hide any early shift. Judge the result weeks after the last planned visit, not after the first. If nothing has changed by then, ask the doctor whether another product family fits your goal better, such as HA for dryness or PDLLA for firmness.